Top overall draft pick Cade Cunningham of the Detroit Pistons will miss Wednesday's season-opening game against the visiting Chicago Bulls, the team indicated on its injury report.
Cunningham has been plagued by a minor ankle sprain that he sustained early in training camp. The 20-year-old guard missed all four of Detroit's preseason games.
Pistons general manager Troy Weaver said prior to Wednesday's game that Cunningham may miss the team's upcoming three-game road trip to Chicago, Atlanta and Philadelphia.
That would put Cunningham in line to make his NBA debut at home on Oct. 30 against the Orlando Magic.
"He's pretty much day-to-day, but we need to ramp him up and get some conditioning going and get him acclimated to going full speed in 5-on-5," Weaver said. "Hopefully, we'll get him back sooner than later, but I would anticipate hopefully seeing him when we get back off the road."
Cunningham averaged 20.1 points, 6.2 rebounds and 3.5 assists last season at Oklahoma State. He won Big 12 Player of the Year honors during his lone season with the Cowboys, leading the team in scoring, assists, steals (43) and 3-point baskets (62).
Forwards Isaiah Livers (foot) and Chris Smith (knee) will also miss Wednesday's game for the Pistons. Guard Coby White (shoulder) is out for the Bulls.