LOS ANGELES -- The Avengers assembled in full force at the box office this weekend.
"Avengers: Infinity War" took North America by storm, opening with $250 million in 4,474 theaters. While numbers could fluctuate before an official tally comes in on Monday, that would surpass "Star Wars: The Force Awakens" for the biggest domestic opening weekend of all time. "The Force Awakens" bowed with $248 million in 2015.
The superhero tentpole, which cost between $300 million and $400 million, opened worldwide with $630 million, making it the highest global opening weekend of all time, even without China debuting this weekend.
Prior to "Infinity War," the original "Avengers" had the highest opening to date for a Marvel film, debuting with $207.4 million. Its sequel, "Age of Ultron," launched with $191 million. The first movie earned $623 million in North America, while the second made $459 million.
Joe and Anthony Russo directed from a script by Christopher Markus and Stephen McFeely. "Infinity War" picks up two years after the events of "Captain America: Civil War" with the Avengers teaming up with the Guardians of the Galaxy to stop the evil Thanos (Josh Brolin) from inter-galactic dominance.
The heroic ensemble cast includes Robert Downey Jr.'s Iron Man, Chris Hemsworth's Thor, Chris Evans' Captain America, Scarlett Johansson's Black Widow, Chadwick Boseman's Black Panther, Chris Pratt's Star Lord, Benedict Cumberbatch's Doctor Strange, and Mark Ruffalo's Hulk.
With no other films opening in the wake of "Infinity War," Paramount Pictures' "A Quiet Place" secured second place with $10.6 million in 3,565 locations. The thriller -- directed by John Krasinski and co-starring Krasinski and Emily Blunt -- continues its impressive run with a domestic total of $148 million in four weeks. Due to the film's monster success, Paramount's head Jim Gianopulos announced a sequel was in the works.
In third place, STX's "I Feel Pretty" scored $8 million from 3,440 theaters in its second weekend. That brings the North American tally on Amy Schumer's latest comedy to $29 million.
Meanwhile, Dwayne Johnson's "Rampage" dropped down to the fourth slot, earning $7.1 million in 3,508 locations. The Warner Bros. actioner has made $77.9 million domestically in its three weeks of release.
Rounding out the weekend is another Marvel title, "Black Panther." In its 11th weekend, the tentpole made $4.6 million, bringing its domestic total to $688 million. Globally, "Black Panther" has collected $1.3 billion. With "Infinity War's" massive debut, Marvel's 19 titles have collectively grossed $15 billion worldwide.
"Infinity War" has ignited a spark in the box office. Prior to this weekend, the year to date box office was down 2.8 percent. After this weekend, the 2018 box office is up 3.2 percent compared to 2017, according to comScore.
"'Avengers: Infinity War' demonstrated yet another Marvel superhero power," Paul Dergarabedian, an analyst at comScore, said. "The ability to reverse a downtrending box office year with a single knockout punch and literally change the box office fortunes of Hollywood almost overnight."